Respiratory coinfections in COVID-19 patients evaluated by BioFire Pneumonia Panel

نویسندگان

چکیده

Abstract Background Routine administration of antibacterials in patients with Covid-19 has been a subject debate, no solid data about the true prevalence respiratory coinfections different geographic areas. The aim current study was to identify admitted hospital and its genetic resistance pattern using multiplex polymerase chain reaction (PCR). Results included 40 patients, 32 males (80%) 8 (20%) females mean age 59.3 ± 12.6. Half had bacterial documented by pneumonia (PN) panel. most common isolate Klebsiella e (10/20, 50%), followed Acinetobacter calcoaceticus baumanni complex (7/20, 35%). Regarding resistance, thirteen (13/20, 65%) isolates were proven extended spectrum beta lactamase (ESBL)-producing Enterobacteriaceae. Thirteen carbapenemase-producing organisms testing positive for New Delhi metallo-β-lactamase (NDM), oxacillinase β-lactamases (OXA-48), Verona Integron-Encoded Metallo-β-Lactamase (VIM) 35%; 5/20, 25%; 1/20, 5%, respectively). four isolated Staphylococcus aureus methicillin-resistant (4/20, 20%). Conclusion In our cohort, there 50% rate coinfection severe ICU high rates gram-negative bacteria that required escalation represented challenge clinicians.

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ژورنال

عنوان ژورنال: Egyptian Journal of Bronchology

سال: 2021

ISSN: ['1687-8426', '2314-8551']

DOI: https://doi.org/10.1186/s43168-021-00077-8